Velasof – Epclusa (Sofosbuvir and Velpatasvir Tablets)

Velasof – Sofosbuvir and Velpatasvir Tablets

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Sofosbuvir/Velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. It combines sofosbuvir and velpatasvir. It is more than 90% effective for hepatitis C genotypes one through six. It also works for hepatitis C in those who also have cirrhosis or HIV/AIDS. It is taken by mouth.

In March 2020, sofosbuvir/velpatasvir was approved for use in the United States to treat hepatitis C virus (HCV) in children ages six years and older or weighing at least 37 pounds (17 kilograms) with any of the six HCV genotypes—or strains—without cirrhosis (liver disease) or with mild cirrhosis. Sofosbuvir/velpatasvir in combination with ribavirin is indicated for the treatment of children six years and older or weighing at least 37 pounds with severe cirrhosis.

The combination is generally well tolerated. Common side effects include headaches, feeling tired, trouble sleeping, and nausea. It has not been studied in pregnant women or during breastfeeding. Greater care is required in those who are also infected with hepatitis B. Sofosbuvir works by blocking the NS5B protein and velpatasvir works by blocking the NS5A protein.

Sofosbuvir/velpatasvir was approved for medical use in the United States and in Europe in 2016. It is on the World Health Organization’s List of Essential Medicines.


Velasof Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection.

Velasof Tablet should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results.

The common side effects of this medicine are tiredness and headache. You should drink plenty of fluid and eat a healthy diet to prevent or overcome the side effects. Before taking the medicine, inform your doctor if you are taking any other medicines or supplements.


  • Treatment of Chronic hepatitis C virus (HCV) infection


In Treatment of Chronic hepatitis C virus (HCV) infection

Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). When the infection moves into a long-lasting stage, it is called chronic hepatitis C virus infection. Velasof Tablet helps reduce the number of hepatitis C virus by preventing it from spreading in your body. This helps control the infection and helps you recover faster. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor.


Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Velasof

  • Headache
  • Tiredness


Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Velasof Tablet may be taken with or without food, but it is better to take it at a fixed time.


Velasof Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.